The Science Behind CDR’s Skin-Protecting Benefits

Dr. Shawn Talbott (Ph.D., CNS, LDN, FACSM, FACN, FAIS) has gone from triathlon struggler to gut-brain guru! With a Ph.D. in Nutritional Biochemistry, he's on a mission to boost everyday human performance through the power of natural solutions and the gut-brain axis.

Best Future YouHarnessing Your Body’s Biochemistry to Achieve Balance in Body, Mind, and Spirit

My 13th book, Best Future You, is out!

Over the next several weeks, I’ll be posting excerpts from the book and blogging frequently about the main concept in the book – which is the idea of harnessing your body’s internal cellular biochemistry to achieve true balance in body, mind, and spirit – and in doing so, help you to become your “Best Future You” in terms of how you look, how you feel, and how you perform on every level.

Chapter 7 – Look Your Best

CDR Offers Multi-Faceted Skin Solutions

Recall from above that we perceive as “aging” is actually a complicated and multifaceted phenomenon related to skin breakdown and repair—a cyclical process that we scientists refer to as “tissue turnover.” In the case of skin, we call it “collagen turnover.” The most effective solution to a multifaceted problem is a multifaceted solution, and that’s exactly what topical CDR activation is all about.

Today, the scientific community accepts the fact that chronic cellular stress leads to a rapid breakdown in a variety of tissues, including skin. Cellular stress in skin cells inevitably leads to skin problems, such as wrinkles, acne, and uneven skin tone. CDR pathways regulate our body’s response to cellular stress and numerous studies have shown that both topical and internal/systemic activation of the CDR pathway can have a wide range of beneficial effects on skin, including reduced rates of skin cancers, protection from ultraviolet radiation, reduced inflammation, enhanced barrier function, and improved wound healing.

The Science Behind CDR’s Skin-Protecting Benefits

In a series of human clinical studies and laboratory studies (isolated skin samples and DNA analysis) CDR-activating herbs such as turmeric, pine bark, quercetin, green tea, brassica, and plantain have been shown to improve skin tone, reduce wrinkles, and generally enhance youthful appearance. In one human clinical study, topical application of CDR-activating herbals showed a dramatic improvement in key beauty benefits, including an extremely high percentage of women who felt that their skin was improved in the following ways: looking smoother, younger, firmer, more even tone, and with fewer wrinkles. These studies indicate a profound ability of CDR-activating herbal blends to treat both intrinsic and extrinsic aging, thus truly delivering on the promise of improving skin on the outside and on the inside. In a series of laboratory studies, isolated skin samples (explants) were investigated to understand the biochemical and genetic mechanisms underlying such rapid and dramatic clinical benefits, American and French researchers treated isolated skin samples daily with CDR-activating herbs and plant extracts. Findings showed clear evidence of the herbs/extracts to :

  • Increase CDR pathway activation in skin (thus improving biochemical resistance to oxidative stress)
  • Boost skin protection from ultraviolet light exposure (by reducing genetic DNA damage)
  • Fight the signs of aging through all layers of the skin (6-7 cellular layers)


The future of science and medicine is targeting the CDR pathways to not only protect our health, but also to actively improve how we feel/look/perform. CDR activation, especially when optimally synergistic in nature, allows you to enjoy enhanced anti-aging benefits for a new level of wellness and vitality.

The last chapter covered how CDR activation can help us to Feel Your Best – and the next chapter covers how CDR activation can help us to Perform Your Best. I want to end this “Look Your Best” chapter with a short list of the primary benefits of CDR activation for skin health:

  • Minimizes inflammation, irritation and redness
  • Reduces wrinkles and improves skin tone
  • Safeguards against free radical/oxidative stress
  • Protects against UV radiation exposure
  • Maintains integrity of key skin structural components
  • Minimizes risk of skin cancers and other conditions

Thanks for reading – be sure to tune in for the next installment where we’ll move into Chapter 8 = Perform Your Best!

Shawn M Talbott, PhD, CNS, LDN, FACSM, FAIS, FACN
Nutritional Biochemist and Author
801-915-1170 (mobile)


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The Secret of Vigor – How to Overcome Burnout, Restore Biochemical Balance, and Reclaim Your Natural Energy
Killer at Large – Why Obesity is America’s Greatest Threat – an award-winning documentary film exploring the causes and solutions underlying the American obesity epidemic
The Cortisol Connection – Why Stress Makes You Fat and Ruins Your Health (Hunter House)
The Cortisol Connection Diet – The Breakthrough Program to Control Stress and Lose Weight (Hunter House)
Cortisol Control and the Beauty Connection – The All-Natural Inside-Out Approach to Reversing Wrinkles, Preventing Acne, And Improving Skin Tone (Hunter House)
Natural Solutions for Pain-Free Living – Lasting Relief for Flexible Joints, Strong Bones and Ache-Free Muscles (Chronicle Publishers – Currant Books)
The Immune Miracle – The All-Natural Approach for Better Health, Increased Energy and Improved Mood (GLH Nutrition, 2012)
A Guide to Understanding Dietary Supplements – an Outstanding Academic Text of 2004 (Haworth Press)
About the Author

Exercise physiologist (MS, UMass Amherst) and Nutritional Biochemist (PhD, Rutgers) who studies how lifestyle influences our biochemistry, psychology and behavior - which kind of makes me a "Psycho-Nutritionist"?!?!

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